ICAM5 antibody

Catalog No. ABIN7229006

The Rabbit Polyclonal anti-ICAM5 antibody (ABIN7229006) specifically detects ICAM5 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for ICAM5 antibody (ABIN7229006)

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ICAM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ICAM5 Antibody

Purpose: Rabbit Anti-ICAM5 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ICAM5 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ICAM5 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Alternative Name: ICAM5

Background: Intercellular adhesion molecule 5, ICAM-5, TelencephalinICAM5 (Intercellular Adhesion Molecule 5) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and ECM-receptor interaction. The protein encoded by ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.

Molecular Weight: 101kD

Gene ID: 7087

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location