IFI16 antibody (AA 700-780)

Catalog No. ABIN7221668

This anti-IFI16 antibody is a Rabbit Polyclonal antibody detecting IFI16 in WB and ELISA. Suitable for Human.

Quick Overview for IFI16 antibody (AA 700-780) (ABIN7221668)

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFI16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IFI16 Antibody

Binding Specificity: AA 700-780

Purpose: IFI-16 Polyclonal Antibody

Specificity: IFI-16 Polyclonal Antibody detects endogenous levels of IFI-16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human IFI-16 at AA range: 700-780

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IFI16

Target: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Alternative Name: IFI-16

Background: Rabbit Anti-IFI-16 Polyclonal Antibody,IFI16, IFNGIP1, Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator,IFI16 encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,Gamma-interferon-inducible protein 16

Molecular Weight: observerd band 88kDa

Gene ID: 3428

UniProt: Q16666

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome