IL15RA antibody (AA 70-150)

Catalog No. ABIN7221810

The Rabbit Polyclonal anti-IL15RA antibody (ABIN7221810) specifically detects IL15RA in WB and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for IL15RA antibody (AA 70-150) (ABIN7221810)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL15RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL15RA Antibody

Binding Specificity: AA 70-150

Purpose: IL-15Rα Polyclonal Antibody

Specificity: IL-15Rα Polyclonal Antibody detects endogenous levels of IL-15Rα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human IL-15Ralpha at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL-15Ralpha

Background: Rabbit Anti-IL-15Rα Polyclonal Antibody,IL15RA, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD antigen CD215,IL15RA encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.,Interleukin-15 receptor subunit alpha

Molecular Weight: observerd band 32kDa

Gene ID: 3601

UniProt: Q13261

Pathways: JAK-STAT Signaling