IL17RA antibody (AA 110-190)

Catalog No. ABIN7220792

This Rabbit Polyclonal antibody specifically detects IL17RA in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for IL17RA antibody (AA 110-190) (ABIN7220792)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RA Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-IL-17Rα Polyclonal Antibody

Specificity: IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IL-17Ralpha at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL-17Ralpha

Background: IL17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD antigen CD217Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 90kD

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome