IL-8 antibody (C-Term)

Catalog No. ABIN7212178

The Mouse Monoclonal anti-IL-8 antibody (Clone 13F8) (ABIN7212178) specifically detects IL-8 in IHC and IF. The antibody is reactive with Human samples.

Quick Overview for IL-8 antibody (C-Term) (ABIN7212178)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: 13F8

Product Details anti-IL-8 Antibody

Binding Specificity: C-Term

Purpose: Mouse Anti-IL-8 Mouse Monoclonal Antibody (13F8)

Specificity: IL-8 protein detects endogenous levels of IL8.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic C-TERM Peptide of IL-8

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-200,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL-8

Background: IL8The protein encoded by CXCL8 (C-X-C motif chemokine ligand 8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. CXCL8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. CXCL8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

Molecular Weight: 11kD

Gene ID: 3576

UniProt: P10145

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy