JDP2 antibody (pThr148)

Catalog No. ABIN7219448

The Rabbit Polyclonal anti-JDP2 antibody (ABIN7219448) specifically detects JDP2 in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for JDP2 antibody (pThr148) (ABIN7219448)

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JDP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-JDP2 Antibody

Binding Specificity: pThr148

Purpose: Rabbit Anti-JDP2 (phospho Thr148) Polyclonal Antibody

Specificity: Phospho-JDP2 (T148) Polyclonal Antibody detects endogenous levels of JDP2 protein only when phosphorylated at T148.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human JDP2 Phospho-Thr148

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for JDP2

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Alternative Name: JDP2

Background: JDP2, Jun dimerization protein 2Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Gene ID: 122953

UniProt: Q8WYK2

Pathways: Chromatin Binding