JDP2 antibody

Catalog No. ABIN7219450

This Rabbit Polyclonal antibody specifically detects JDP2 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for JDP2 antibody (ABIN7219450)

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JDP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-JDP2 Antibody

Purpose: Rabbit Anti-JDP2 Polyclonal Antibody

Specificity: JDP2 Polyclonal Antibody detects endogenous levels of JDP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human JDP2 around the non-phosphorylation site of T148

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for JDP2

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Alternative Name: JDP2

Background: JDP2, Jun dimerization protein 2Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.

Molecular Weight: 22kD

Gene ID: 122953

UniProt: Q8WYK2

Pathways: Chromatin Binding