JUP antibody (AA 670-750)

Catalog No. ABIN7213990

This anti-JUP antibody is a Rabbit Polyclonal antibody detecting JUP in WB, IF, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for JUP antibody (AA 670-750) (ABIN7213990)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-JUP Antibody

Binding Specificity: AA 670-750

Purpose: Catenin-γ Polyclonal Antibody

Specificity: Catenin-γ Polyclonal Antibody detects endogenous levels of Catenin-γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Catenin-gamma at AA range: 670-750

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: Catenin-gamma

Background: Rabbit Anti-Catenin-γ Polyclonal Antibody,JUP, CTNNG, DP3, Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3,JUP encodes a major cytoplasmic protein (junction plakoglobin) which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.,Junction plakoglobin

Molecular Weight: observerd band 82kDa

Gene ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location