JAM2 antibody (Internal Region)

Catalog No. ABIN7217780

This Rabbit Polyclonal antibody specifically detects JAM2 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for JAM2 antibody (Internal Region) (ABIN7217780)

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-JAM2 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-JAM-B Polyclonal Antibody

Specificity: JAM-B Polyclonal Antibody detects endogenous levels of JAM-B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human JAM-B

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for JAM2

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Alternative Name: JAM-B

Background: JAM2, C21orf43, VEJAM, Junctional adhesion molecule B, JAM-B, Junctional adhesion molecule 2, JAM-2, Vascular endothelial junction-associated molecule, VE-JAM, CD322JAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 33kD

Gene ID: 58494

UniProt: P57087