KSR2 antibody (AA 640-720)

Catalog No. ABIN7221194

The Rabbit Polyclonal anti-KSR2 antibody (ABIN7221194) specifically detects KSR2 in ELISA, WB, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for KSR2 antibody (AA 640-720) (ABIN7221194)

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KSR2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-KSR2 Antibody

Binding Specificity: AA 640-720

Purpose: Rabbit Anti-Ksr2 Polyclonal Antibody

Specificity: Ksr2 Polyclonal Antibody detects endogenous levels of Ksr2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Ksr2 at AA range: 640-720

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KSR2

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Alternative Name: Ksr2

Background: KSR2, Kinase suppressor of Ras 2, hKSR2Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Molecular Weight: 108kD

Gene ID: 283455

UniProt: Q6VAB6