KLF8 antibody (AA 160-240)

Catalog No. ABIN7219298

The Rabbit Polyclonal anti-KLF8 antibody is suitable to detect KLF8 in samples from Human and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for KLF8 antibody (AA 160-240) (ABIN7219298)

Target: KLF8 (Kruppel-Like Factor 8 (KLF8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF8 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-KLF8 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-KLF8 Polyclonal Antibody

Specificity: KLF8 Polyclonal Antibody detects endogenous levels of KLF8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human KLF8 at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KLF8

Target: KLF8 (Kruppel-Like Factor 8 (KLF8))

Alternative Name: KLF8

Background: KLF8, BKLF3, ZNF741, Krueppel-like factor 8, Basic krueppel-like factor 3, Zinc finger protein 741KLF8 encodes Kruppel like factor 8 which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

Gene ID: 11279

UniProt: O95600