LARP1 antibody

Catalog No. ABIN7229354

The Rabbit Polyclonal anti-LARP1 antibody is suitable to detect LARP1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for LARP1 antibody (ABIN7229354)

Target: LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LARP1 Antibody

Purpose: Rabbit Anti-LARP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LARP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LARP1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LARP1

Target: LARP1 (La Ribonucleoprotein Domain Family, Member 1 (LARP1))

Alternative Name: LARP1

Background: La-related protein 1, La ribonucleoprotein domain family member 1LARP1 (La Ribonucleoprotein Domain Family Member 1) is a Protein Coding gene. Among its related pathways are Translational Control. RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex Associates with the mRNA 5cap in an MTOR-dependent manner and associates with mRNAs containing a 5 terminal oligopyrimidine (5TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5TOP, thereby regulating cell growth and proliferation Positively regulates the replication of dengue virus

Molecular Weight: 120kD

Gene ID: 23367

UniProt: Q6PKG0

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection