LEFTY1 antibody (C-Term)

Catalog No. ABIN7218790

The Rabbit Polyclonal anti-LEFTY1 antibody is suitable to detect LEFTY1 in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for LEFTY1 antibody (C-Term) (ABIN7218790)

Target: LEFTY1 (Left-Right Determination Factor 1 (LEFTY1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEFTY1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LEFTY1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-Lefty Polyclonal Antibody

Specificity: Lefty Polyclonal Antibody detects endogenous levels of Lefty protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Lefty

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LEFTY1

Target: LEFTY1 (Left-Right Determination Factor 1 (LEFTY1))

Alternative Name: Lefty

Background: LEFTY1, LEFTB, LEFTYB, Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B, LEFTY2, EBAF, LEFTA, LEFTYA, TGFB4, PSEC0024, Left-right determination factor 2, Endometrial bleeding-associated factor, Left-riLEFTY1 encodes a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. LEFTY1 is closely linked to both a related family member and a related pseudogene.

Molecular Weight: 40kD

Gene ID: 10637, 7044

UniProt: O75610, O00292