LEPREL1 antibody

Catalog No. ABIN7230456

The Rabbit Polyclonal anti-LEPREL1 antibody (ABIN7230456) specifically detects LEPREL1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for LEPREL1 antibody (ABIN7230456)

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LEPREL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LEPREL1 Antibody

Purpose: Rabbit Anti-P3H2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of P3H2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human P3H2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LEPREL1

Target: LEPREL1 (Leprecan Like Protein 1 (LEPREL1))

Alternative Name: P3H2

Background: Prolyl 3-hydroxylase 2, Leprecan-like protein 1, Myxoid liposarcoma-associated protein 4P3H2 gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 77kD

Gene ID: 55214

UniProt: Q8IVL5