LASP1 antibody (AA 90-130)

Catalog No. ABIN7229402

This Rabbit Polyclonal antibody specifically detects LASP1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LASP1 antibody (AA 90-130) (ABIN7229402)

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LASP1 Antibody

Binding Specificity: AA 90-130

Purpose: Rabbit Anti-LIM and SH3 domain protein 1 Polyclonal Antibody

Specificity: This antibody detects endogenous levels of LIM and SH3 domain protein 1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LIM and SH3 domain protein 1 protein at AA range: 90-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LASP1

Target: LASP1 (LIM and SH3 Protein 1 (LASP1))

Alternative Name: LIM and SH3 domain protein 1

Background: LIM and SH3 domain protein 1, LASP-1, Metastatic lymph node gene 50 protein, MLN 50LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.

Molecular Weight: 38kD

Gene ID: 3927

UniProt: Q14847