LY96 antibody

Catalog No. ABIN7229486

The Rabbit Polyclonal anti-LY96 antibody (ABIN7229486) specifically detects LY96 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for LY96 antibody (ABIN7229486)

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LY96 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LY96 Antibody

Purpose: Rabbit Anti-LY96 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of LY96 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human LY96 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LY96

Target: LY96 (Lymphocyte Antigen 96 (LY96))

Alternative Name: LY96

Background: Lymphocyte antigen 96, Ly-96, ESOP-1, Protein MD-2LY96 encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that LY96 may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. LY96 (Lymphocyte Antigen 96) is a Protein Coding gene. Diseases associated with LY96 include Intestinal Botulism and Wound Botulism. Among its related pathways are Activated TLR4 signalling and Diseases of Immune System.

Molecular Weight: 17kD

Gene ID: 23643

UniProt: Q9Y6Y9

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades