MRAP antibody (AA 20-100)
Quick Overview for MRAP antibody (AA 20-100) (ABIN7229750)
Target
See all MRAP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-100
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Purpose
- MRAP Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of MRAP protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human MRAP protein at AA range: 20-100
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MRAP (Melanocortin 2 Receptor Accessory Protein (MRAP))
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Alternative Name
- MRAP
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Background
- Rabbit Anti-MRAP Polyclonal Antibody,Melanocortin-2 receptor accessory protein, B27, Fat cell-specific low molecular weight protein, Fat tissue-specific low MW protein,MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. Diseases associated with MRAP include Glucocorticoid Deficiency 2 and Familial Glucocorticoid Deficiency. MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in MRAP have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described.,MRAP
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Molecular Weight
- observerd band 18kDa
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Gene ID
- 56246
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UniProt
- Q8TCY5
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Pathways
- Brown Fat Cell Differentiation
Target
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