MAGEA3 antibody (AA 190-270)

Catalog No. ABIN7229512

This Rabbit Polyclonal antibody specifically detects MAGEA3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MAGEA3 antibody (AA 190-270) (ABIN7229512)

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAGEA3 Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-MAGA3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MAGA3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MAGA3 protein at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAGEA3

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Alternative Name: MAGA3

Background: Melanoma-associated antigen 3, Antigen MZ2-D, Cancer/testis antigen 1.3, CT1.3, MAGE-3 antigenMAGEA3 (MAGE Family Member A3) is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of MAGEA3 family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGEA3 is a Protein Coding gene. Diseases associated with MAGEA3 include Melanoma and Hepatocellular Carcinoma. An important paralog of this gene is MAGEA6.

Molecular Weight: 34kD

Gene ID: 4102

UniProt: P43357