MFGE8 antibody

Catalog No. ABIN7229652

The Rabbit Polyclonal anti-MFGE8 antibody (ABIN7229652) specifically detects MFGE8 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MFGE8 antibody (ABIN7229652)

Target: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MFGE8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MFGE8 Antibody

Purpose: Rabbit Anti-MFGM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MFGM protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MFGM protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MFGE8

Target: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Alternative Name: MFGM

Background: Lactadherin, Breast epithelial antigen BA46, HMFG, MFGM, Milk fat globule-EGF factor 8, MFG-E8, SED1MFGE8 encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. MFGE8 (Milk Fat Globule-EGF Factor 8 Protein) is a Protein Coding gene. Diseases associated with MFGE8 include Opisthorchiasis and Anal Paget's Disease. Among its related pathways are Integrins in angiogenesis and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.

Molecular Weight: 42kD

Gene ID: 4240

UniProt: Q08431

Pathways: SARS-CoV-2 Protein Interactome