MRPL39 antibody (AA 270-350)

Catalog No. ABIN7223252

This Rabbit Polyclonal antibody specifically detects MRPL39 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MRPL39 antibody (AA 270-350) (ABIN7223252)

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL39 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MRPL39 Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-MRP-L39 Polyclonal Antibody

Specificity: MRP-L39 Polyclonal Antibody detects endogenous levels of MRP-L39 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human MRP-L39 at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL39

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Alternative Name: MRP-L39

Background: MRPL39, C21orf92, MRPL5, RPML5, MSTP003, PRED22, 39S ribosomal protein L39, mitochondrial, L39mt, MRP-L39, 39S ribosomal protein L5, mitochondrial, L5mt, MRP-L5Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL39 (mitochondrial ribosomal protein L39) encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to MRPL39 is found on chromosome 5q.

Molecular Weight: 39kD

Gene ID: 54148

UniProt: Q9NYK5