MRPS2 antibody (AA 210-290)

Catalog No. ABIN7222974

The Rabbit Polyclonal anti-MRPS2 antibody is suitable to detect MRPS2 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for MRPS2 antibody (AA 210-290) (ABIN7222974)

Target: MRPS2 (Mitochondrial Ribosomal Protein S2 (MRPS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS2 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-MRP-S2 Polyclonal Antibody

Specificity: MRP-S2 Polyclonal Antibody detects endogenous levels of MRP-S2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human MRP-S2 at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPS2

Target: MRPS2 (Mitochondrial Ribosomal Protein S2 (MRPS2))

Alternative Name: MRP-S2

Background: MRPS2, CGI-91, 28S ribosomal protein S2, mitochondrial, MRP-S2, S2mtMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS2 encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene.

Molecular Weight: 33kD

Gene ID: 51116

UniProt: Q9Y399

Pathways: SARS-CoV-2 Protein Interactome