MUC16 antibody (AA 13280-13360)

Catalog No. ABIN7225966

The Rabbit Polyclonal anti-MUC16 antibody is suitable to detect MUC16 in samples from Human. It has been validated for IHC and WB.

Quick Overview for MUC16 antibody (AA 13280-13360) (ABIN7225966)

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC16 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-MUC16 Antibody

Binding Specificity: AA 13280-13360

Purpose: Rabbit Anti-Mucin 16 Polyclonal Antibody

Specificity: Mucin 16 Polyclonal Antibody detects endogenous levels of Mucin 16 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Mucin 16 at AA range: 13280-13360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MUC16

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Alternative Name: Mucin 16

Background: MUC16, CA125, Mucin-16, MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller ""subunits"" being described by some investigators. The antibody recognizes the C-term of MUC16.

Gene ID: 94025

UniProt: Q8WXI7