Myosin IA antibody (AA 370-450)

Catalog No. ABIN7229852

The Rabbit Polyclonal anti-Myosin IA antibody (ABIN7229852) specifically detects Myosin IA in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Myosin IA antibody (AA 370-450) (ABIN7229852)

Target: Myosin IA (MYO1A)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin IA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Myosin IA Antibody

Binding Specificity: AA 370-450

Purpose: Rabbit Anti-MYO1A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MYO1A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MYO1A protein at AA range: 370-450

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Myosin IA

Target: Myosin IA (MYO1A)

Alternative Name: MYO1A

Background: Unconventional myosin-Ia, Brush border myosin I, BBM-I, BBMI, Myosin I heavy chain, MIHC-PMYO1A (Myosin IA) is a Protein Coding gene. Diseases associated with MYO1A include Dfna48 Nonsyndromic Hearing Loss And Deafness and Deafness, Autosomal Dominant 48. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. MYO1A encodes a member of the myosin superfamily. The protein represents an unconventional myosin, it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors.

Molecular Weight: 114kD

Gene ID: 4640

UniProt: Q9UBC5

Pathways: Sensory Perception of Sound