NCR3 antibody (AA 80-160)

Catalog No. ABIN7220924

The Rabbit Polyclonal anti-NCR3 antibody (ABIN7220924) specifically detects NCR3 in ELISA and WB. The antibody is reactive with Human and Rat samples.

Quick Overview for NCR3 antibody (AA 80-160) (ABIN7220924)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-NCR3 Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-NKp30 Polyclonal Antibody

Specificity: NKp30 Polyclonal Antibody detects endogenous levels of NKp30 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NKp30 at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: NKp30

Background: NCR3, 1C7, LY117, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NKp30, CD antigen CD337The natural cytotoxicity triggering receptor 3 encoded by NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 22kD

Gene ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process