NPY1R antibody (AA 190-270)

Catalog No. ABIN7222812

This Rabbit Polyclonal antibody specifically detects NPY1R in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NPY1R antibody (AA 190-270) (ABIN7222812)

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPY1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NPY1R Antibody

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-NPY1-R Polyclonal Antibody

Specificity: NPY1-R Polyclonal Antibody detects endogenous levels of NPY1-R protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NPY1-R at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NPY1R

Target: NPY1R (Neuropeptide Y Receptor Y1 (NPY1R))

Alternative Name: NPY1-R

Background: NPY1R, NPYR, NPYY1, Neuropeptide Y receptor type 1, NPY1-RNPY1R belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.

Molecular Weight: 48kD

Gene ID: 4886

UniProt: P25929

Pathways: Negative Regulation of Hormone Secretion, Feeding Behaviour