NIPBL antibody (AA 560-640)

Catalog No. ABIN7230008

This Rabbit Polyclonal antibody specifically detects NIPBL in IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for NIPBL antibody (AA 560-640) (ABIN7230008)

Target: NIPBL (Nipped-B like Protein (NIPBL))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIPBL antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NIPBL Antibody

Binding Specificity: AA 560-640

Purpose: Rabbit Anti-NIPBL Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NIPBL protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NIPBL protein at AA range: 560-640

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NIPBL

Target: NIPBL (Nipped-B like Protein (NIPBL))

Alternative Name: NIPBL

Background: Nipped-B-like protein, Delangin, SCC2 homologNIPBL (NIPBL, Cohesin Loading Factor) is a Protein Coding gene. Diseases associated with NIPBL include Cornelia De Lange Syndrome 1 and Nipbl-Related Cornelia De Lange Syndrome. Among its related pathways are Cell Cycle, Mitotic and Mitotic Telophase/Cytokinesis. NIPBL encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation.

Molecular Weight: 308kD

Gene ID: 25836

UniProt: Q6KC79

Pathways: Sensory Perception of Sound, Stem Cell Maintenance