NFAT5 antibody (pSer1197)

Catalog No. ABIN7219120

The Rabbit Polyclonal anti-NFAT5 antibody is suitable to detect NFAT5 in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for NFAT5 antibody (pSer1197) (ABIN7219120)

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFAT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NFAT5 Antibody

Binding Specificity: pSer1197

Purpose: Rabbit Anti-NFAT5 (phospho Ser1197) Polyclonal Antibody

Specificity: Phospho-NFAT5 (S1197) Polyclonal Antibody detects endogenous levels of NFAT5 protein only when phosphorylated at S1197.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NFAT5 Phospho-Ser1197

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NFAT5

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Alternative Name: NFAT5

Background: NFAT5, KIAA0827, TONEBP, Nuclear factor of activated T-cells 5, NF-AT5, T-cell transcription factor NFAT5, Tonicity-responsive enhancer-binding protein, TonE-binding protein, TonEBPThe product of NFAT5 is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 10725

UniProt: O94916

Pathways: RTK Signaling, WNT Signaling