NCOR2 antibody (AA 100-180)

Catalog No. ABIN7223338

The Rabbit Polyclonal anti-NCOR2 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect NCOR2 in samples from Human, Mouse and Rat.

Quick Overview for NCOR2 antibody (AA 100-180) (ABIN7223338)

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NCOR2 Antibody

Binding Specificity: AA 100-180

Purpose: TRAC-1 Polyclonal Antibody

Specificity: TRAC-1 Polyclonal Antibody detects endogenous levels of TRAC-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human TRAC-1 at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for NCOR2

Target: NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))

Alternative Name: TRAC-1

Background: Rabbit Anti-TRAC-1 Polyclonal Antibody,RNF125, E3 ubiquitin-protein ligase RNF125, RING finger protein 125, T-cell RING activation protein 1, TRAC-1,RNF125 (ring finger protein 125) encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.,E3 ubiquitin-protein ligase RNF125

Molecular Weight: observerd band 26kDa

Gene ID: 54941

UniProt: Q96EQ8

Pathways: Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha