NUP88 antibody (AA 330-410)

Catalog No. ABIN7217698

The Rabbit Polyclonal anti-NUP88 antibody is suitable to detect NUP88 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for NUP88 antibody (AA 330-410) (ABIN7217698)

Target: NUP88 (Nucleoporin 88kDa (NUP88))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP88 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NUP88 Antibody

Binding Specificity: AA 330-410

Purpose: Rabbit Anti-Nup88 Polyclonal Antibody

Specificity: Nup88 Polyclonal Antibody detects endogenous levels of Nup88 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Nup88 at AA range: 330-410

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NUP88

Target: NUP88 (Nucleoporin 88kDa (NUP88))

Alternative Name: Nup88

Background: NUP88, Nuclear pore complex protein Nup88, 88 kDa nucleoporin, Nucleoporin Nup88The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 83kD

Gene ID: 4927

UniProt: Q99567

Pathways: SARS-CoV-2 Protein Interactome