PON3 antibody

Catalog No. ABIN7230730

The Rabbit Polyclonal anti-PON3 antibody is suitable to detect PON3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PON3 antibody (ABIN7230730)

Target: PON3 (Paraoxonase 3 (PON3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PON3 Antibody

Purpose: Rabbit Anti-PON3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PON3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PON3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PON3

Target: PON3 (Paraoxonase 3 (PON3))

Alternative Name: PON3

Background: Serum paraoxonase/lactonase 3PON3 is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described, however, only one has been fully characterized.

Molecular Weight: 38kD

Gene ID: 5446

UniProt: Q15166

Pathways: Monocarboxylic Acid Catabolic Process