PEX12 antibody (AA 180-260)

Catalog No. ABIN7230590

The Rabbit Polyclonal anti-PEX12 antibody is suitable to detect PEX12 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PEX12 antibody (AA 180-260) (ABIN7230590)

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PEX12 Antibody

Binding Specificity: AA 180-260

Purpose: Rabbit Anti-PEX12 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PEX12 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PEX12 protein at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PEX12

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Alternative Name: PEX12

Background: Peroxisome assembly protein 12, Peroxin-12, Peroxisome assembly factor 3, PAF-3PEX12 (Peroxisomal Biogenesis Factor 12) is a Protein Coding gene. Diseases associated with PEX12 include Peroxisome Biogenesis Disorder 3B and Peroxisome Biogenesis Disorder 3A. Among its related pathways are Peroxisome. PEX12 belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).

Molecular Weight: 39kD

Gene ID: 5193

UniProt: O00623