PEX12 antibody (AA 290-359)

Catalog No. ABIN7269246

The Rabbit Polyclonal anti-PEX12 antibody (ABIN7269246) specifically detects PEX12 in WB. The antibody is reactive with Human samples.

Quick Overview for PEX12 antibody (AA 290-359) (ABIN7269246)

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PEX12 Antibody

Binding Specificity: AA 290-359

Purpose: PEX12 Rabbit pAb

Sequence: YNSDSPLLPK MKTVCPLCRK TRVNDTVLAT SGYVFCYRCV FHYVRSHQAC PITGYPTEVQ HLIKLYSPEN

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-359 of human PEX12 (NP_000277.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PEX12

Target: PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))

Alternative Name: PEX12

Background: This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).,PEX12,PAF-3,PBD3A,Signal Transduction,PEX12

Molecular Weight: 40kDa

Gene ID: 5193

UniProt: O00623