PPAN antibody

Catalog No. ABIN7231532

The Rabbit Polyclonal anti-PPAN antibody (ABIN7231532) specifically detects PPAN in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PPAN antibody (ABIN7231532)

Target: PPAN (Peter Pan Homolog (PPAN))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPAN Antibody

Purpose: Rabbit Anti-SSF1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SSF1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SSF1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPAN

Target: PPAN (Peter Pan Homolog (PPAN))

Alternative Name: SSF1

Background: Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homologThe protein encoded by PPAN is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of PPAN was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.

Molecular Weight: 52kD

Gene ID: 56342

UniProt: Q9NQ55