PDE1A antibody

Catalog No. ABIN7230550

The Rabbit Polyclonal anti-PDE1A antibody is suitable to detect PDE1A in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for PDE1A antibody (ABIN7230550)

Target: PDE1A (Phosphodiesterase 1A (PDE1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDE1A Antibody

Purpose: Rabbit Anti-PDE1A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PDE1A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PDE1A protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDE1A

Target: PDE1A (Phosphodiesterase 1A (PDE1A))

Alternative Name: PDE1A

Background: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, Cam-PDE 1A, 61 kDa Cam-PDE, hCam-1PDE1A (Phosphodiesterase 1A) is a Protein Coding gene. Among its related pathways are Calcium signaling pathway and DAG and IP3 signaling. Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates.

Molecular Weight: 58kD

Gene ID: 5136

UniProt: P54750

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma