PLCD1 antibody (AA 90-170)

Catalog No. ABIN7230678

The Rabbit Polyclonal anti-PLCD1 antibody (ABIN7230678) specifically detects PLCD1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLCD1 antibody (AA 90-170) (ABIN7230678)

Target: PLCD1 (phospholipase C, delta 1 (PLCD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLCD1 Antibody

Binding Specificity: AA 90-170

Purpose: Rabbit Anti-PLCD1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PLCD1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PLCD1 protein at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLCD1

Target: PLCD1 (phospholipase C, delta 1 (PLCD1))

Alternative Name: PLCD1

Background: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C-III, PLC-III, Phospholipase C-delta-1, PLC-delta-1PLCD1 encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PLCD1.

Molecular Weight: 83kD

Gene ID: 5333

UniProt: P51178

Pathways: WNT Signaling, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process