PMVK antibody

Catalog No. ABIN7230716

This Rabbit Polyclonal antibody specifically detects PMVK in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for PMVK antibody (ABIN7230716)

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMVK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PMVK Antibody

Purpose: Rabbit Anti-PMVK Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PMVK protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PMVK protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PMVK

Target: PMVK (Phosphomevalonate Kinase (PMVK))

Alternative Name: PMVK

Background: Phosphomevalonate kinase, PMKase, hPMKPMVK gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 21kD

Gene ID: 10654

UniProt: Q15126