Plakophilin 2 antibody (AA 610-690)

Catalog No. ABIN7216602

The Rabbit Polyclonal anti-Plakophilin 2 antibody (ABIN7216602) specifically detects Plakophilin 2 in WB, ELISA and IHC. The antibody is reactive with Human and Rat samples.

Quick Overview for Plakophilin 2 antibody (AA 610-690) (ABIN7216602)

Target: Plakophilin 2 (PKP2)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Plakophilin 2 Antibody

Binding Specificity: AA 610-690

Purpose: Rabbit Anti-Plakophilin 2 Polyclonal Antibody

Specificity: Plakophilin 2 Polyclonal Antibody detects endogenous levels of Plakophilin 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Plakophilin 2 at AA range: 610-690

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Plakophilin 2

Target: Plakophilin 2 (PKP2)

Alternative Name: Plakophilin 2

Background: PKP2, Plakophilin-2PKP2 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Molecular Weight: 97kD

Gene ID: 5318

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection