PDGFRA antibody
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- Target See all PDGFRA Antibodies
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PDGFRA antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purpose
- PDGFRα Mouse Monoclonal Antibody (7A3)
- Specificity
- PDGFRα protein detects endogenous levels of PDGFRA.
- Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
- Immunogen
- Synthetic Peptide of PDGFRalpha at AA range of 1010-1090
- Clone
- 7A3
- Isotype
- IgG1
- Top Product
- Discover our top product PDGFRA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
- Comment
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Primary Antibody
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Target
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- Alternative Name
- PDGFRalpha (PDGFRA Products)
- Synonyms
- AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
- Background
- Mouse Anti-PDGFRα Mouse Monoclonal Antibody (7A3),PDGFRA,PDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that PDGFRA plays a role in organ development, wound healing, and tumor progression. Mutations in PDGFRA have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.,PDGFRA
- Molecular Weight
- observerd band 180kDa
- Gene ID
- 5156
- UniProt
- P16234
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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