PDGFC antibody (AA 61-110)

Catalog No. ABIN7230564

The Rabbit Polyclonal anti-PDGFC antibody (ABIN7230564) specifically detects PDGFC in IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PDGFC antibody (AA 61-110) (ABIN7230564)

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFC antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PDGFC Antibody

Binding Specificity: AA 61-110

Purpose: Rabbit Anti-PDGF-C Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PDGF-C

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PDGF-C protein at AA range: 61-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDGFC

Target: PDGFC (Platelet-Derived Growth Factor C (PDGFC))

Alternative Name: PDGF-C

Background: Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-EThe protein encoded by PDGFC is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. PDGFC product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for PDGFC.

Gene ID: 56034

UniProt: Q9NRA1

Pathways: RTK Signaling, Platelet-derived growth Factor Receptor Signaling