PLAGL1 antibody (AA 280-360)

Catalog No. ABIN7217534

This Rabbit Polyclonal antibody specifically detects PLAGL1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for PLAGL1 antibody (AA 280-360) (ABIN7217534)

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAGL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLAGL1 Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-ZAC1 Polyclonal Antibody

Specificity: ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ZAC1 at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLAGL1

Target: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Alternative Name: ZAC1

Background: PLAGL1, LOT1, ZAC, Zinc finger protein PLAGL1, Lost on transformation 1, LOT-1, Pleiomorphic adenoma-like protein 1, Tumor supressor ZACPLAGL1 encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.

Molecular Weight: 50kD

Gene ID: 5325

UniProt: Q9UM63