Plexin C1 antibody (Internal Region)

Catalog No. ABIN7218756

The Rabbit Polyclonal anti-Plexin C1 antibody is suitable to detect Plexin C1 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for Plexin C1 antibody (Internal Region) (ABIN7218756)

Target: Plexin C1 (PLXNC1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plexin C1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Plexin C1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CD232 Polyclonal Antibody

Specificity: CD232 Polyclonal Antibody detects endogenous levels of CD232 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD232

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Plexin C1

Target: Plexin C1 (PLXNC1)

Alternative Name: CD232

Background: PLXNC1, VESPR, Plexin-C1, Virus-encoded semaphorin protein receptor, CD232PLXNC1 encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The plexin C1 and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene.

Molecular Weight: 175kD

Gene ID: 10154

UniProt: O60486