PKD1 antibody (pTyr463)

Catalog No. ABIN7223538

The Rabbit Polyclonal anti-PKD1 antibody (ABIN7223538) specifically detects PKD1 in IHC, ELISA, WB and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PKD1 antibody (pTyr463) (ABIN7223538)

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PKD1 Antibody

Binding Specificity: pTyr463

Purpose: Rabbit Anti-PKD1 (phospho Tyr463) Polyclonal Antibody

Specificity: Phospho-PKD1 (Y463) Polyclonal Antibody detects endogenous levels of PKD1 protein only when phosphorylated at Y463.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PKD1 Phospho-Tyr463

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PKD1

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Alternative Name: PKD1

Background: PRKD1, PKD, PKD1, PRKCM, Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-muPRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion.

Molecular Weight: 130kD

Gene ID: 5587

UniProt: Q15139

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location