POLM antibody (AA 210-290)

Catalog No. ABIN7217760

The Rabbit Polyclonal anti-POLM antibody (ABIN7217760) specifically detects POLM in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for POLM antibody (AA 210-290) (ABIN7217760)

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLM Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-DNA Pol μ Polyclonal Antibody

Specificity: DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human DNA Pol mu at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Alternative Name: DNA Pol mu

Background: POLM, polmu, DNA-directed DNA/RNA polymerase mu, Pol Mu, Terminal transferasePOLM (Polymerase (DNA) Mu) is a Protein Coding gene. Among its related pathways are Platinum Pathway, Pharmacokinetics/Pharmacodynamics and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include DNA-directed DNA polymerase activity and DNA polymerase activity. An important paralog of this gene is POLB. Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.

Molecular Weight: 54kD

Gene ID: 27434

UniProt: Q9NP87

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response