POLRMT antibody

Catalog No. ABIN7231168

The Rabbit Polyclonal anti-POLRMT antibody (ABIN7231168) specifically detects POLRMT in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for POLRMT antibody (ABIN7231168)

Target: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLRMT antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLRMT Antibody

Purpose: Rabbit Anti-RPOM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RPOM protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RPOM protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLRMT

Target: POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

Alternative Name: RPOM

Background: DNA-directed RNA polymerase, mitochondrialPOLRMT encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. POLRMT (RNA Polymerase Mitochondrial) is a Protein Coding gene. Diseases associated with POLRMT include Autosomal Dominant Progressive External Ophthalmoplegia. Among its related pathways are Pyrimidine metabolism (KEGG) and Organelle biogenesis and maintenance.

Molecular Weight: 135kD

Gene ID: 5442

UniProt: O00411