KCNK4 antibody (AA 310-390)

Catalog No. ABIN7217364

The Rabbit Polyclonal anti-KCNK4 antibody is suitable to detect KCNK4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for KCNK4 antibody (AA 310-390) (ABIN7217364)

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNK4 Antibody

Binding Specificity: AA 310-390

Purpose: Rabbit Anti-TRAAK Polyclonal Antibody

Specificity: TRAAK Polyclonal Antibody detects endogenous levels of TRAAK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TRAAK at AA range: 310-390

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KCNK4

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Alternative Name: TRAAK

Background: KCNK4, TRAAK, Potassium channel subfamily K member 4, TWIK-related arachidonic acid-stimulated potassium channel protein, TRAAK, Two pore potassium channel KT4.1, Two pore K(+) channel KT4.1KCNK4 encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The potassium channel subfamily K member 4 homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. Potassium channel subfamily K member 4 is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.

Molecular Weight: 45kD

Gene ID: 50801

UniProt: Q9NYG8