PMCH antibody (AA 112-161)

Catalog No. ABIN7230714

The Rabbit Polyclonal anti-PMCH antibody (ABIN7230714) specifically detects PMCH in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PMCH antibody (AA 112-161) (ABIN7230714)

Target: PMCH (Pro-Melanin-Concentrating Hormone (PMCH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMCH antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PMCH Antibody

Binding Specificity: AA 112-161

Purpose: Rabbit Anti-PMCH Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PMCH

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PMCH protein at AA range: 112-161

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PMCH

Target: PMCH (Pro-Melanin-Concentrating Hormone (PMCH))

Alternative Name: PMCH

Background: Pro-MCHPMCH encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include melanin-concentrating hormone (MCH), neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). Melanin-concentrating hormone is a 19-amino acid neuropeptide that stimulates hunger and may additionally regulate energy homeostasis, reproductive function, and sleep. Pseudogenes of PMCH have been identified on chromosome 5. PMCH (Pro-Melanin Concentrating Hormone) is a Protein Coding gene. Diseases associated with PMCH include Hypersomnia and Byssinosis. Among its related pathways are Signaling by GPCR and RET signaling.

Gene ID: 5367

UniProt: P20382

Pathways: Carbohydrate Homeostasis, Feeding Behaviour