Prokineticin Receptor 2 antibody (AA 20-100)

Catalog No. ABIN7230670

The Rabbit Polyclonal anti-Prokineticin Receptor 2 antibody is suitable to detect Prokineticin Receptor 2 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for Prokineticin Receptor 2 antibody (AA 20-100) (ABIN7230670)

Target: Prokineticin Receptor 2 (PROKR2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prokineticin Receptor 2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Prokineticin Receptor 2 Antibody

Binding Specificity: AA 20-100

Purpose: Rabbit Anti-PKR2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PKR2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PKR2 protein at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Prokineticin Receptor 2

Target: Prokineticin Receptor 2 (PROKR2)

Alternative Name: PKR2

Background: Prokineticin receptor 2 , PK-R2, G-protein coupled receptor 73-like 1, G-protein coupled receptor I5E, GPR73b, GPRg2Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins.

Molecular Weight: 42kD

Gene ID: 128674

UniProt: Q8NFJ6

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma