Prolactin Receptor antibody (AA 80-160)

Catalog No. ABIN7230782

The Rabbit Polyclonal anti-Prolactin Receptor antibody is suitable to detect Prolactin Receptor in samples from Human. It has been validated for WB and ELISA.

Quick Overview for Prolactin Receptor antibody (AA 80-160) (ABIN7230782)

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Prolactin Receptor Antibody

Binding Specificity: AA 80-160

Purpose: Rabbit Anti-PRLR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PRLR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PRLR protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Background: Prolactin receptor, PRL-RPRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for PRLR, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Molecular Weight: 68kD

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus