PMEPA1 antibody (AA 1268-1341)

Catalog No. ABIN7227086

This Rabbit Polyclonal antibody specifically detects PMEPA1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for PMEPA1 antibody (AA 1268-1341) (ABIN7227086)

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMEPA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PMEPA1 Antibody

Binding Specificity: AA 1268-1341

Purpose: Rabbit Anti-TMEPAI Polyclonal Antibody

Specificity: The antibody detects endogenous TMEPAI.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1268-1341

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PMEPA1

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Alternative Name: TMEPAI

Background: Transmembrane prostate androgen-induced protein, Solid tumor-associated 1 proteinPMEPA1 (prostate transmembrane protein, androgen induced 1) encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of PMEPA1 is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of PMEPA1 may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PMEPA1.

Molecular Weight: 36kD

Gene ID: 56937

UniProt: Q969W9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway