PRSS2 antibody (AA 40-120)

Catalog No. ABIN7231936

The Rabbit Polyclonal anti-PRSS2 antibody (ABIN7231936) specifically detects PRSS2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PRSS2 antibody (AA 40-120) (ABIN7231936)

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRSS2 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-TRY2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TRY2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TRY2 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Alternative Name: TRY2

Background: Anionic trypsinogen, Serine protease 2, Trypsin IIPRSS2 belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Molecular Weight: 27kD

Gene ID: 5645

UniProt: P07478